Question:
BBC News Tuesday, 6 March, 2001 Allergy hope for asthmatic children Simple measures to reduce exposure to a range of allergy triggers and pollutants could cut the number of asthmatic children by almost 40%, says research. The US scientists believe that more than 500,000 children under the age of six in that country would not have developed the disease if they lived in "allergen-free" houses. They suggest a shortlist of potential triggers that could be removed by families where there is a history of asthma. These include pets such as dogs or cats, gas cookers and cigarette smoke. All of these are believed to increase the chances of a child who is genetically predisposed to asthma developing the disease, which can prove disabling, or even fatal in a very few cases. If all three were eliminated, say the team from the Children’s Hospital Medical Center of Cincinnati, the number of asthma cases would be reduced by 39% . Dr Bruce Lanphear, who led the study, looked at 8,257 children younger than six. He said: "Children who had a history of allergies to a pet were 24 times more likely to have doctor-diagnosed asthma. Pet rescue "Parents need to consider carefully the risks and benefits of owning a pet, particularly during early childhood and especially if there is a maternal history of an allergic condition. "Residential exposures account for more excess cases of childhood asthma than having a parent with a history of atopy (the predisposition to develop allergy)." He added: "These and other data demonstrate that children’s health is inextricably linked with housing." Impracticalities highlighted However, Professor Ashley Woodcock, a professor of Respiratory Medicine at the North West Lung Centre in Manchester, said it was impractical to eliminate all these allergens from the home. He said: "I’m a dog lover myself, and I know how much they become part of the family. "However, parents who have a child with asthma should consider having their child allergy-tested for the pet, and if they are allergic, consider getting rid of the pet. "And certainly smoking near a child with asthma is tantamount to child abuse." The research is published in the journal Pediatrics.
Response:
In myexperience spaying of a cat increases the quantity of cat hair loss ie far more cat hairs collect on furniture and carpets wherever the cat goes From Fliveya
Response:
In myexperience spaying of a cat increases the quantity of cat hair loss ie far more cat hairs collect on furniture and carpets wherever the cat goes From Fliveya
Which makes no difference since the allergy is to an enzyme in the skin oils and saliva – not the fur. There is no ‘Army of One’ in the word: ‘Team’
Response:
But the presence of the fallen fur can physically inhibit breathing by making a patient feel claustrophobic probably making the allergy worse
Response:
But the presence of the fallen fur can physically inhibit breathing by making a patient feel claustrophobic probably making the allergy worse
Go away. You are a troll. Nobody can be this stupid by accident. There is no ‘Army of One’ in the word: ‘Team’
Response:
But the presence of the fallen fur can physically inhibit breathing by making a patient feel claustrophobic probably making the allergy worse
What’s that word? Oh, right, "Ploink!"
Response:
You have obviosly never ever suffered with daily picking upof cat fur have you ??? you seem obsessed with scrolling down to the base of your communications on this board and making rude remarks well that may have been someone of the surname Campbell Personally id do no tlike Campblells soups so that makes me even more inclined to dislike and distrust your communications Please excuse me if the rude remarks were made by others I have many health problems but try to trat myself as a whole and probably treatment will include deleting your asthma board from my set of favourite places and maybe Scotland also From Fliveya
Response:
hahahaha – Hide quoted text — Show quoted text – You have obviosly never ever suffered with daily picking upof cat fur have you ??? you seem obsessed with scrolling down to the base of your communications on this board and making rude remarks well that may have been someone of the surname Campbell Personally id do no tlike Campblells soups so that makes me even more inclined to dislike and distrust your communications Please excuse me if the rude remarks were made by others I have many health problems but try to trat myself as a whole and probably treatment will include deleting your asthma board from my set of favourite places and maybe Scotland also From Fliveya
Response:
Australian Broadcasting Corporation Radio National with Norman Swan Helicobacter pylori Monday 11 October 1999 Summary: Recently published results of a trial to get rid of the ulcer germ Helicobacter pylori in people who had non ulcer dyspepsia. Norman Swan: OK then, there’s your first chance to test drive some of these ideas. The guinea pig is Nick Talley, who’s Professor of Medicine at the University of Sydney at Nepean. He and his colleagues have published a paper in this week’s edition of the prestigious New England Journal of Medicine. It reports the results of a trial to get rid of the ulcer germ Helicobacter pylori in people who had what’s called ‘non ulcer dyspepsia.’ Nick Talley: It’s a symptom complex where people have pain or discomfort and that can include nausea or belching sometimes, bloating, fullness. And they’ve had these symptoms usually chronically for a long time, and they’re troubled by them. And these symptoms are not explained by a peptic ulcer or any other obvious structural cause when specific testing is done. Norman Swan: And it’s quite common, isn’t it? Nick Talley: It’s pretty common. It probably affects about 20% of Australians all told, if you look at the figures from epidemiological studies, and it’s the same actually all over the world. Norman Swan: Now why blame H pylori, this ulcer bug, when I thought that really nobody knew what the cause of non-ulcer dyspepsia was? Nick Talley: Well nobody really knows what the cause is, but we know that perhaps somewhere from one in five to one in two people with non-ulcer dyspepsia actually have this bug, and in fact with this bug, have inflammation in their stomach. And I guess the issue then is does the bug cause the symptoms in at least those people who have the infection. That’s certainly been a question that has vexed investigators and patients for a long time now. Norman Swan: So what did you do in the study? Nick Talley: In the study, we randomised patients to either triple therapy, which is standard antibiotics plus an acid suppression drug for a period of 14 days, or placebo, which is a dummy preparation with no active component. And then we looked at a year later whether we’d relieved the symptoms in people who had received these treatments. The goal was to see whether curing the infection would cure the dyspepsia, cure the pain or discomfort in the stomach area. Norman Swan: So I suppose the first question to ask before we find out about the symptoms is whether or not you managed to cure the infection in the people who had it. Nick Talley: We certainly cured the vast majority. Sure, there were a few people around about 10%, who failed the treatment standards, but we cured the vast majority with the antibiotic treatment. And so that approach certainly was effective in curing the infection. But curing the symptoms is a different story. Norman Swan: You didn’t have success there? Nick Talley: Unfortunately no; it depends on what you define as success. If you look at the result it’s about one in five actually got complete symptom relief with the antibiotic treatment. But unfortunately one in five on the placebo preparation also got complete relief. Norman Swan: So there is no difference between the two. What then is the recommendation? Nick Talley: Well, it’s very difficult. If you find the infection, detect the infection with various tests that we have available, my belief is you need to discuss with each individual the pros and cons of treating the infection. I mean the pros are you can prevent peptic ulcer in some people with non-ulcer dyspepsia, and we know that about 5% at least of patients with non-ulcer dyspepsia go on to get an ulcer. So that’s a lot in a sense, and treating the infection can help prevent this. Norman Swan: So if you know you’ve got it, and you do nothing, there’s a small chance you could go on to have an ulcer? Nick Talley: Correct, and that’s one of the reasons I personally believe treating the infection is of value in non-ulcer dyspepsia, even though it doesn’t relieve the symptoms. But there are cons too: you can have reactions to the treatment, and they can be serious very occasionally, and that’s certainly an issue that patients need to know about. And also there are some people who believe you may precipitate other health problems if you get rid of the bacteria in large numbers of people. For example there have been suspicions that some people might develop reflux disease if they have the infection treated. Now is only a suspicion, it’s not really established, but certainly it’s a concern and that concern remains to be solved. Norman Swan: And I suppose the threshold question is that should the doctor do the diagnostic test for H pylori in the first place? Nick Talley: Well my view is if you don’t wish to treat the infection, if you find it, then don’t do the test. But if you do do the test, before you do it, you need to discuss with the patient again the advantages and disadvantages of treating the infection. Because if they’ve got it, in most cases you’ll end up treating it anyway, at least in clinical practice. Norman Swan: What’s left then for treating non-ulcer dyspepsia, this bloated feeling? Nick Talley: Well if you’ve got pain as your major problem, some people really just complain of epigastric stomach-type pain. Norman Swan: Epigastric being the top of the abdomen there, just below the rib-cage. Nick Talley: Correct. If they complain of that as the main symptom, then acid suppression treatments can be helpful, and I think that should be first line treatment in that group who have established non-ulcer dyspepsia. If on the other hand it’s a bloated feeling or a discomfort or a fullness, then drugs that speed up stomach emptying, they also can be helpful in at least some people with the problem. And then there are some really exciting new approaches being developed for non-ulcer dyspepsia. For example, there is a new approach for people who can’t eat a normal meal, who feel full soon after they eat a normal meal, and in that sub-group of people there’s evidence that their stomach doesn’t relax properly; the top part of their stomach fails to relax. And some drugs, for example the anti-migraine drug sumatriptan that seems to be potentially useful in that sub-group. It remains to be established in large trials, but it looks very promising from the small studies that are available now. So there are some new approaches, but still it’s a difficult problem to treat for some people. Norman Swan: And who should go on to have an endoscopy, or a look inside? Nick Talley: Well I think people who present for the first time in middle age, over the age of 50, I think they should have an endoscopy, just to make sure there’s not some serious disease there. And obviously people who have alarm features, symptoms like weight loss, or difficulty swallowing, or recurrent vomiting, if you have those kinds of symptoms, then I believe you should have an endoscopy to check out you don’t have something more serious. But again, most people who are investigated with this, will not have a serious problem found. Norman Swan: Professor Nick Talley. Reference: Talley N.J. et al. Absence of benefit of eradicating Helicobacter pylori in patients with non-ulcer dyspepsia. New England Journal of Medicine 1999;341:1106-1111. Norman Swan: Well, did that answer the five questions for you? Guests: Dr. Nick Talley Professor of Medicine University of Sydney, Gastroenterologist, Nepean Hospital, Penrith NSW 2750
Response:
Australian Broadcasting Corporation Radio National with Norman Swan Paracetamol and Asthma Monday 27 March 2000 Summary: Recent research has found that the more people use paracetamol the greater the incidence of asthma and its severity. Norman Swan: Welcome to the program. Today, how some people with asthma might be able to help their headaches and their wheezing at the same time. And speaking of the lungs, why is it that a high proportion of women who smoke are able to give up cigarettes for the duration of their pregnancy, get beyond all the withdrawal symptoms, yet go back to it after the baby’s born? It seems that these women can’t win. Whether their partners smoke or not, they’re not too helpful. Plus, treating genes to treat ovarian cancer. Research just published has found that the more people use paracetamol, the greater the instance of asthma and its severity. The work was done by a team in London, and included Dr Seif Shaheen. Thanks for your time today Seif, tonight, your time. Now the question is why paracetamol? A very different drug from aspirin which is known to be dangerous for some people with asthma. Seif Shaheen: That’s correct. It’s been known for a while that in a minority of asthmatic patients, aspirin and related anti-inflammatory painkillers such as Ibuprofen can cause sensitivity reactions, manifested as asthma attacks. So asthma patients are generally advised to avoid those painkillers. And the associations we found with frequent paracetamol use really are new. Norman Swan: And why did you head that way? What made you think that paracetamol could be a problem. It’s nothing like aspirin. Seif Shaheen: We were carrying out a large study of diet and asthma in south London, really focusing on the possible role of antioxidants in asthma. There’s a belief that antioxidants in the lung may protect the lung against damaging pollutants in the air and help to dampen down asthma inflammation in the airways. And that was the focus of the study. But we did set out to look for possible associations with paracetamol use, because of work that has been done in the past in animal experiments, which have shown that paracetamol can deplete the lung in animals, of an important antioxidant found in the ways, called glutathione So we were setting out to look for this association as part of our broader study of diet and asthma. Norman Swan: But it’s pretty hard to study, since everybody takes a couple of paracetamol from time to time. Seif Shaheen: Well they do. We asked about frequency of use, and in fact there was a wide variation. But about 20% of our asthmatic adults in our survey reported that they were using paracetamol on a daily or weekly basis, and 5%, one in 20, were saying that they used it every day. And it was with daily and weekly use that we found this quite strong association with asthma symptoms and with more severe symptoms in people who already had asthma. Norman Swan: Now is it an association, or is it cause and effect? Seif Shaheen: It’s an association, and it’s important to emphasise that the nature of our study design cannot allow us to really say that one is causing the other. There are a number of different possible interpretations. Norman Swan: Let me tease out just exactly what the association is. Is it between whether or not you’re an asthmatic, or how severe your asthma is, and just go into some detail about how much paracetamol? Seif Shaheen: It’s both. So what we found was that people who reported taking daily or weekly paracetamol, particularly daily paracetamol, were more likely to report asthma symptoms than were people who never used it. And if you just then looked within the people who had asthma symptoms, we found that again, frequent use, daily and weekly use, was associated with more severe symptoms. Norman Swan: And why were they taking the paracetamol, because that could be more important than the paracetamol itself? Seif Shaheen: That’s a good question, and we were surprised to find that so many people were taking it so frequently. So what we did is, we actually went back and we sent another questionnaire to the frequent users of paracetamol, asking them exactly that question: what were the indications for their frequent use? By far and away the commonest reason was for headache, followed by migraine and muscular and skeletal aches and pains. And that’s in keeping with other surveys of analgesic use. Headache is by far and away the commonest reason why people take painkillers in the general population. Norman Swan: It’s almost as if you’ve uncovered a chronic pain population here, if they’re taking paracetamol on a daily basis for headaches. Seif Shaheen: Well yes, other surveys have shown that perhaps some people use analgesics, painkillers, excessively, and there is quite a well-recognised syndrome of, I’m sure you know, that in people who are troubled by headaches, that if they use analgesics too much, that can actually make the headaches worse, and they get into a vicious cycle. So our feeling is that if some of these very frequent daily users of this painkiller, paracetamol, are able to cut down, then this may be beneficial for their asthma. Norman Swan: And it might help their headaches too, paradoxically? Seif Shaheen: It might do, yes. Norman Swan: And what was the increased risk of asthma or severe asthma? Seif Shaheen: We found that compared with never-users, people who weren’t taking paracetamol at all, that weekly users were 80% more likely to report asthma symptoms. Daily users were more than twice as likely as never-users, to report having asthma symptoms. Norman Swan: And will you be able to get a linear story here, with the asthmatic before they started the paracetamol? Seif Shaheen: It’s difficult. Our survey was really a snapshot picture. We were looking at one point time, at asthmatic and non-asthmatic adults, and asking them what do they usually use in terms of their painkillers. It’s not possible for us to know how long they’d had their asthma for, and whether long-term analgesic use had preceded the development of asthma in the first place. We just couldn’t do that in our survey. Norman Swan: Asthma is part of a trilogy of conditions called atopic, that’s allergic rhinitis, hay fever, and eczema. Did you find any associated with those two other conditions? Seif Shaheen: We didn’t ask about eczema. One of the problems in adults we find, is that unlike in children where eczema, as you rightly say, is usually an allergic disease, in adults the term ‘eczema’ is often misunderstood, and it’s difficult to identify true allergic eczema because a lot of adults have contact dermatitis, to do with the use of jewellery and things. So that’s a more difficult condition to pick up in adults just by asking them a question. But we did ask about rhinitis. In other words, hay fever like symptoms, or rhinitis symptoms related to house dust mite, and we found a similar association; we found a positive association between frequent use of paracetamol and rhinitis, even in adults who did not have asthma. Norman Swan: How does this boil down to advice for people with asthma, because they’ve already been warned, or they should have been warned by their doctor to avoid aspirin-like drugs and non-steroidal anti-inflammatory drugs because they could bring on an asthma attack for different reasons. If they’re on panadol or paracetamol I should say, because of that advice, really, what do they do? Seif Shaheen: Well I can understand that they may feel confused, and I think there’s two important messages that I would want to communicate to them. Firstly, they are right, if they have asthma, to carry on avoiding aspirin and other related anti-inflammatory analgesics such as Ibuprofen Because of the potential risk, albeit in a minority of asthma patients, of quite severe sensitivity reactions which manifests as severe asthma attacks, it is possible that some asthma patients may have been tested for this sensitivity, so they may know already that in fact aspirin is safe to take, but as general advice, we would still emphasise that asthma patients should not take aspirin, or Ibuprofen type drugs. If they are frequent users of paracetamol, particularly if they’re taking it on a daily basis, we would advise them if possible to see whether they can cut down on that use, because it is possible that their asthma symptoms might improve as a result of that. Norman Swan: Thank you very much, Dr Shaheen for joining us on The Health Report. Seif Shaheen: My pleasure. Norman Swan: Dr Seif Shaheen is a Clinical Epidemiologist in the Department of Public Health Sciences at King’s College and St Thomas’ School of Medicine in London. Reference: Shaheen S et al. Frequent paracetamol use and asthma in adults. Thorax 2000;55:266-270 Guests: Dr. Seif Shaheen Clinical Epidemiologist, Department of Public Health Sciences, Kings College and St. Thomas’s School of Medicine, London, U.K.
Response:
Creation of smarter mice could lead to drugs for human brain disorders By JEFF BARNARD September 1, 1999 Scientists have engineered gene that produces more intelligent mice, a research breakthrough that that could lead to human babies with higher IQs and drugs to treat Alzheimer’s disease and stroke. Inserting an extra gene, researchers produced a strain of mice – nicknamed "doogies" – that excelled in a range of tasks such as recognizing a Lego piece they’d encountered before, learning the location of a hidden underwater platform and recognizing cues that they were about to receive a mild shock. The improved learning and memory came from increased production of a brain protein called NR2B. The mice carried the enhanced abilities into adulthood, when learning ability and memory naturally taper off, and passed their heightened learning abilities on to their offspring. "This points to the possibility that enhancement of learning and memory or even IQ is feasible through genetic means, through genetic engineering," said Joe Z. Tsien, the assistant professor of molecular biology at Princeton University who led the research team. The findings, published in Thursday’s issue of Nature, indicate that a common mechanism lies at the root of all learning and identifies the protein NR2B as a key to brain function. The study could lead to a drug to treat memory disorders, such as Alzheimer’s, by increasing NR2B levels, Tsien added. Production of NR2B protein normally decreases with age, correlating with the loss of memory and learning ability commonly experienced by older people, Tsien said. The new work on mice represents a breakthrough in understanding how the brain functions at the molecular level, said Robert Malenka, a psychiatrist and behavioral sciences specialist at Stanford University School of Medicine. "To jump from this very elegant molecular work in a mouse model to humans is a very, very big jump," said Malenka, who was not involved in the research. "Nevertheless, it is a jump we can make and will make eventually. When we jump to humans, it will probably be a lot more complicated." One complication is the risk that any drug that would increase NR2B levels could also increase the risk of stroke, because both stroke and learning are related to the same neurological switches in the brain, Malenka added. Ron McKay of the National Institute of Neurological Disorders and Stroke said drug companies are already investigating manipulation of NR2B levels to treat strokes. Any research that illuminates how NR2B works in the brain would be valuable in that work, he said. The prospect of genetically engineering smarter babies raises big ethical questions. "What we are looking at is the baby steps toward a world in which we can design our descendants," said Arthur Caplan, director of the Center for Bioethics at the University of Pennsylvania Health System. "I don’t think that is necessarily bad. Finding ways to repair autism or mental retardation associated with Down syndrome or Alzheimer’s or other disabling neurological diseases is a very good thing." Because of the inherent risks, it makes more sense ethically to begin applying this discovery to treating diseases and disorders, rather than trying to create smarter babies, Caplan added. "I wouldn’t say I would be worried quite yet about seeing hordes of tiny Einsteins in my neighborhood," he said. But just as parents strive to improve their children by sending them to better schools or giving them piano lessons, there will be those who want to genetically enhance their offspring, said Caplan. As in other areas of life, the rich would have an advantage. "We already have a brain gap in this society when some children go to kindergartens that cost $15,000 a year and other children go to kindergartens that don’t have adequate plumbing," he said. Tsien nicknamed the smart mice "Doogie" after the teenage genius in the television show "Doogie Howser, M.D." Using a tiny glass needle, the scientists injected a gene carrying a blueprint for the protein NR2B into the nucleus of a fertilized mouse egg, then implanted the resulting embryo into the uterus of a mother mouse. Mice born with the extra gene made more NR2B than usual in their brains. That extra production boosted mental abilities by enhancing the function of brain-cell switches called NMDA receptors. The results confirm the idea, proposed in 1949, that these switches play a key role in learning. The NMDA switches require two signals to open, which fits in with the idea that learning involves associating pairs of events or facts, like a tone and an electrical shock. Boosting levels of the NR2B protein kept the mouse NMDA switches open longer than usual. "If you associated food with a bell, a voice with a face, a face with a name, these are all associative learning, the major forms of learning in humans," Tsien said. "To associate those things you require some kind of cellular machinery. "It is so nice to convince ourselves that we are working in the right machinery." Top Rated Programs – 1990-1995 Rank Year Program Network 1 1990-91 Cheers NBC 2 1990-91 60 Minutes CBS 3 1990-91 Roseanne ABC 4 1990-91 A Different World NBC 5 1990-91 The Cosby Show NBC 6 1990-91 Murphy Brown CBS 7 1990-91 Empty Nest NBC 8 1990-91 America’s Funniest Home Videos ABC 9 1990-91 Monday Night Football ABC 10 1990-91 The Golden Girls NBC 11 1990-91 Designing Women CBS 12 1990-91 Murder, She Wrote CBS 13 1990-91 America’s Funniest People ABC 14 1990-91 Full House ABC 15 1990-91 Family Matters ABC 16 1990-91 Unsolved Mysteries NBC 17 1990-91 Matlock NBC 18 1990-91 Coach ABC 19 1990-91 Who’s the Boss? ABC 20 1990-91 CBS Sunday Night Movie CBS 21 1990-91 In the Heat of the Night NBC 22 1990-91 Major Dad CBS 23 1990-91 L.A. Law NBC 24 1990-91 Doogie Howser, M.D. ABC 25 1990-91 Grand NBC Sixteen-year-old Dr. Douglas "Doogie" Howser is a resident at Eastman Medical Center in Los Angeles, having conquered high school in nine weeks, graduated from Princeton at the age of 10 and from medical school at 14. The boy genius is a sweetly earnest and accomplished doctor, but he has a lot to learn about life and the emotional and psychological health of his patients and fellow physicians. In this gentle comedy of a boy’s unique journey to manhood, each episode ends with Doogie reflecting on the day’s "lesson" by typing into his electronic diary, his computer. Doogie’s demanding father, also a doctor, and his mother help him maintain an even balance, although they are sometimes as confused as he is by his dual child-man role. Medical associates, often lacking empathy for their inexperienced colleague, keep him on his toes. Doogie’s not-so-bright buddy, Vinnie, is his link with the teen world and, in later episodes, becomes his roommate in an "odd couple" apartment. Making its cable TV premiere, "Doogie Howser, M.D." is the creation of Steven Bochco, better known as the executive producer of harshly realistic police dramas. CAST Doogie Howser: Neil Patrick Harris Dr. David Howser: James B. Sikking Katherine Howser: Belinda Montgomery Vinnie Delpino: Max Casella Dr. Benjamin Canfield: Lawrence Pressman Dr. Jack McGuire: Mitchell Anderson Nurse Curly Spaulding: Kathryn Layng Wanda Plenn: Lisa Dean Ryan Janine Stewart: Lucy Boryer Series Run First Telecast: September 19, 1989 Last Telecast: July 21, 1993 Broadcast History September 1989, ABC, Tuesday 8:30-9:00pm September 1989, ABC, Wednesday 9:30-10:00pm October 1989- February 1992, ABC, Wednesday 9:00-9:30pm February 1992- May 1992, ABC, Wednesday 8:30-9:00pm May 1992- August 1992, ABC, Wednesday 9:00-9:30pm August 1992- March 1993, ABC, Wednesday 8:30-9:00pm June 1993- July 1993, ABC, Wednesday 8:30-9:00pm Classic TV Ratings The Show: 4 Stars The Characters: 4 Stars The Theme Song: 4 Stars Tony Woo, Aussie Doogie Howser! G’day! I am Tony Woo, a young, rich Australian physician. I work at Perth’s largest hospital, and spend lots of time crusin’ cyberspace. Chiropractic’s Doogie Howser Dr. Robert Nab was only 22 years old when he began practicing chiropractic, prompting the nickname "Doogie Howser, DC." He not only started early, he started right. After graduating from Cleveland College of Chiropractic in December 1994, he went into an extended preceptorship, which he considers an excellent experience. The Doogie Howser of business There is no reason to pretend that Matthew McDowell is an average 15-year-old high school sophomore. "After nineteen years of living with my parents, I finally moved into my own place. I answer to no one. Everywhere I look is mine, mine, mine. Be careful what you ask for, you just might get it." Doogie Howser, M.D.
Response:
BBC World Service Plants of Power Experts disscuss how different cultures throughout history have used mind altering plants for intoxication. Plants of Power: how do they work? http://www.bbc.co.uk/worldservice/health/medicinedrugs/plant_05.ram Which plants are produce the chemical substances that make up all major drugs? And just how do these chemicals affect the body? With Dr Randolph Nesse, Professor of Psychiatry at the University of Michigan and co-author of Evolution and Healing:The New Science of Darwinian Medicine and Ethan Nadelmann, head of the Lindesmith Centre, the Open Society Institute’s drug-policy think-tank in New York City. Plants of Power: when is a plant a drug? http://www.bbc.co.uk/worldservice/health/medicinedrugs/plant_04.ram Is coffee a drug? Is sugar a drug? Which substances do different societies around the world view as drugs? With Andrew Sherratt, from the the Ashmolean Museum in Oxford, co-editor of Consuming Habits: Drugs in History and Anthropology. Edward Behr, author of Prohibition: The Years that Changed America. Animal researcher, Dr Ron Siegel author of Intoxications and Fire in the Brain, Dr Andrew Weil and Jonathan Kingdon.
Response:
BBC News Tuesday, 11 April, 2000 M*A*S*H star Linville dies Actor Larry Linville, best known as the whining surgeon Major Frank Burns in the long-running US TV series M*A*S*H, has died aged 60. Linville, who had a cancerous lung removed in 1998, died at the Memorial Sloan-Kettering Cancer Centre in New York, after being admitted suffering from pneumonia. The actor’s long-time manager Larry M Greenberg said: "He was wonderfully refreshing and irreverent but always a very talented and professional guy. He took this cancer thing better than anybody I’ve ever seen." Famous for screen affair Linville, who came from Ojai in California, had been living in New York and is survived by his wife, Deborah. Linville was a original member of the comic drama series M*A*S*H – about a field hospital unit in Korea during the 1950s war – which ran from 1972 to 1983. As Major Burns, he became famous for his affair with head nurse Margaret "Hot Lips" Houlihan, played by Loretta Swit. "My scenes with Loretta were quite extraordinary because we were a team," Linville said in an interview with CBS radio. "We were Mutt and Jeff, Roadrunner and Coyote, whatever, we were a proper pair." Much of the show’s early action revolved around the antics of tent-mates Burns, Hawkeye Pierce – played by Alan Alda – and Trapper John McIntyre – played by Wayne Rogers. Hawkeye and Trappper were the unit’s best doctors and Burns became the foil to their relentless jokes. Cult following Their humour at his expense centred around heaping practical jokes on their hapless colleague, as part of their efforts to keep sane while working close to the front lines. M*A*S*H, which grew out of the movie of the same name, acquired a cult following over its 11 years in production with its irreverent blend of comedy and political commentary. But the show also took on serious topics of war and bloodshed, often seemingly more relevant to the Vietnam War than the conflict in Korea. Linville left M*A*S*H in 1977. He went on to guest star on numerous television series and had roles in Grandpa Goes to Washington, Checking In and Paper Dolls.
Response:
– Hide quoted text — Show quoted text – With a little luck this year I maybe selected for an Oryx depredation hunt. In my past 35 years of hunting have hunted mule deer, whitetail deer, moose, elk, caribou, and several versions of bighorn ram not to mention smallgame like feral hog and of course upland bird. Talking with several hunting friends I am confused about how tough this animal is to bring down. I do understand the differences in the anatomy (i.e. location of the heart/lungs and the spinal cord in the neck). That aside, some say you need to use .338 Win Mag with a 200+ grain bullet because the hide is so thick, other say to can bring it down with a well placed .243 Win (this would be foolish but). I have been out on the range hunting coyote and quail and happened upon an Oryx. They show no fear of man, I’ve been able to walk to within 75 yds and all they do is look and turn away. Since they are not hunted, with the exception of these herd thinning hunts, and the fact that most if not all reside on access controlled military land they show no fear. I have been looking at using either my .280 Rem with a Sierra 160 gr SBT with a MV of about 2600 fps. However, rumor has it that the local military game management person is allowing only .30 cal and above, I’ve talked to him and pointed out that many would like to use 7mm and he received this with some enthusiasm and he said he would conceder 7mm. If the 30 cal rule prevails I’ll use my 300 Win Mag with a Sierra 165 gr SBT giving around 2800 fps. From what I’ve gleaned looking at several books on hunting African
antelope. The Oryx is much tougher than the larger kudu and most writers consider a 7mm at the very bottom of calibers to use and requiring very good shot placement. However given that, it should work. Let boys want pleasure, and men Struggle for power, and women perhaps for fame, And the servile to serve a Leader and the dupes to be duped. Yours is not theirs. "Be Angry at the Sun" Robinson Jeffers Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
With a little luck this year I maybe selected for an Oryx depredation
hunt. Ok, John, I’ll bite, just what in hell is an Oryx anyway ? Mike , just back from an unsuccessful opening day here in Ohio. Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
With a little luck this year I maybe selected for an Oryx depredation hunt. Ok, John, I’ll bite, just what in hell is an Oryx anyway ? Mike , just back from an unsuccessful opening day here in Ohio.
A large African antelope. http://www.awf.org/animals/oryx.html Let boys want pleasure, and men Struggle for power, and women perhaps for fame, And the servile to serve a Leader and the dupes to be duped. Yours is not theirs. "Be Angry at the Sun" Robinson Jeffers Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
With a little luck this year I maybe selected for an Oryx depredation hunt. In my past 35 years of hunting have hunted mule deer, whitetail deer, moose, elk, caribou, and several versions of bighorn ram not to mention smallgame like feral hog and of course upland bird. Talking with several hunting friends I am confused about how tough this animal is to bring down. I do understand the differences in the anatomy (i.e. location of the heart/lungs and the spinal cord in the neck). That aside, some say you need to use .338 Win Mag with a 200+ grain bullet because the hide is so thick, other say to can bring it down with a well placed .243 Win (this would be foolish but). I have been out on the range hunting coyote and quail and happened upon an Oryx. They show no fear of man, I’ve been able to walk to within 75 yds and all they do is look and turn away. Since they are not hunted, with the exception of these herd thinning hunts, and the fact that most if not all reside on access controlled military land they show no fear. I have been looking at using either my .280 Rem with a Sierra 160 gr SBT with a MV of about 2600 fps. However, rumor has it that the local military game management person is allowing only .30 cal and above, I’ve talked to him and pointed out that many would like to use 7mm and he received this with some enthusiasm and he said he would conceder 7mm. If the 30 cal rule prevails I’ll use my 300 Win Mag with a Sierra 165 gr SBT giving around 2800 fps. I would appreciate any input on hunting these animals. Thanks Jack SFC, USA (Ret, 1971-1993) Life member NRA (1969) Life member TSRA (1991) Member USPSA (1990) Member NROI (1991) Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
Interesting reply from DU in Canada. Quite diplomatic in its avoidance of answering your point blank question. A yes or a no is all it needed. They tell you they were founded by help from hunters, and still use hunters funds, but never say if they are against hunting. They did state they are trying to be Canada’s foremost conservation group. Not all conservation groups are pro- hunting. — Mark Life member NAHC, Endowment Life member NRA Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
Several weeks ago I read a post that stated DU Canada was anti hunting. I didn’t believe this so I went to the DU Canada site and asked them point blank; are you or are you not against hunting. Below is their answer. Jack —- SFC, USA (Ret, 1971-1993) Life member NRA (1969) Life member TSRA (1991) Member USPSA (1990) Member NROI (1991) http://home.elp.rr.com/jacksrange —- Dear Jack: Thank you for inquiring about Ducks Unlimited’s position on hunting. Ducks Unlimited Canada proudly acknowledges its hunting heritage. We recognize the ethical and sustainable recreational harvest of waterfowl as a legitimate and acceptable use of a renewable resource. It was conservation minded waterfowl hunters who established Ducks Unlimited in Canada more that 60 years ago. Their desire to ensure the long-term success of waterfowl populations defined Ducks Unlimited’s mandate. Continued support from the hunting community, and that from others interested in conserving wildlife habitat, combined with our proven ability to direct resources towards our mission has helped to establish Ducks Unlimited as the country’s most trusted and respected conservation organization. If you have attended a DU event, you will have witnessed how important hunters are to our organization. Even beyond DU, hunters are significant funders and contributors to conservation efforts across North America. We appreciate you bringing your concerns to us and providing us with an opportunity to respond. Unfortunately, every large, successful organization has its detractors. Luckily, there are individuals like you who question what you believe to be incorrect. Most sincerely, Lauralou Cicierski Communications, Ducks Unlimited Canada Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
– Hide quoted text — Show quoted text – With a little luck this year I maybe selected for an Oryx depredation hunt. In my past 35 years of hunting have hunted mule deer, whitetail deer, moose, elk, caribou, and several versions of bighorn ram not to mention smallgame like feral hog and of course upland bird. Talking with several hunting friends I am confused about how tough this animal is to bring down. I do understand the differences in the anatomy (i.e. location of the heart/lungs and the spinal cord in the neck). That aside, some say you need to use .338 Win Mag with a 200+ grain bullet because the hide is so thick, other say to can bring it down with a well placed .243 Win (this would be foolish but). I have been out on the range hunting coyote and quail and happened upon an Oryx. They show no fear of man, I’ve been able to walk to within 75 yds and all they do is look and turn away. Since they are not hunted, with the exception of these herd thinning hunts, and the fact that most if not all reside on access controlled military land they show no fear. I have been looking at using either my .280 Rem with a Sierra 160 gr SBT with a MV of about 2600 fps. However, rumor has it that the local military game management person is allowing only .30 cal and above, I’ve talked to him and pointed out that many would like to use 7mm and he received this with some enthusiasm and he said he would conceder 7mm. If the 30 cal rule prevails I’ll use my 300 Win Mag with a Sierra 165 gr SBT giving around 2800 fps. From what I’ve gleaned looking at several books on hunting African
antelope. The Oryx is much tougher than the larger kudu and most writers consider a 7mm at the very bottom of calibers to use and requiring very good shot placement. However given that, it should work. Let boys want pleasure, and men Struggle for power, and women perhaps for fame, And the servile to serve a Leader and the dupes to be duped. Yours is not theirs. "Be Angry at the Sun" Robinson Jeffers Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
With a little luck this year I maybe selected for an Oryx depredation
hunt. Ok, John, I’ll bite, just what in hell is an Oryx anyway ? Mike , just back from an unsuccessful opening day here in Ohio. Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
With a little luck this year I maybe selected for an Oryx depredation hunt. Ok, John, I’ll bite, just what in hell is an Oryx anyway ? Mike , just back from an unsuccessful opening day here in Ohio.
A large African antelope. http://www.awf.org/animals/oryx.html Let boys want pleasure, and men Struggle for power, and women perhaps for fame, And the servile to serve a Leader and the dupes to be duped. Yours is not theirs. "Be Angry at the Sun" Robinson Jeffers Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
With a little luck this year I maybe selected for an Oryx depredation hunt. In my past 35 years of hunting have hunted mule deer, whitetail deer, moose, elk, caribou, and several versions of bighorn ram not to mention smallgame like feral hog and of course upland bird. Talking with several hunting friends I am confused about how tough this animal is to bring down. I do understand the differences in the anatomy (i.e. location of the heart/lungs and the spinal cord in the neck). That aside, some say you need to use .338 Win Mag with a 200+ grain bullet because the hide is so thick, other say to can bring it down with a well placed .243 Win (this would be foolish but). I have been out on the range hunting coyote and quail and happened upon an Oryx. They show no fear of man, I’ve been able to walk to within 75 yds and all they do is look and turn away. Since they are not hunted, with the exception of these herd thinning hunts, and the fact that most if not all reside on access controlled military land they show no fear. I have been looking at using either my .280 Rem with a Sierra 160 gr SBT with a MV of about 2600 fps. However, rumor has it that the local military game management person is allowing only .30 cal and above, I’ve talked to him and pointed out that many would like to use 7mm and he received this with some enthusiasm and he said he would conceder 7mm. If the 30 cal rule prevails I’ll use my 300 Win Mag with a Sierra 165 gr SBT giving around 2800 fps. I would appreciate any input on hunting these animals. Thanks Jack SFC, USA (Ret, 1971-1993) Life member NRA (1969) Life member TSRA (1991) Member USPSA (1990) Member NROI (1991) Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
Interesting reply from DU in Canada. Quite diplomatic in its avoidance of answering your point blank question. A yes or a no is all it needed. They tell you they were founded by help from hunters, and still use hunters funds, but never say if they are against hunting. They did state they are trying to be Canada’s foremost conservation group. Not all conservation groups are pro- hunting. — Mark Life member NAHC, Endowment Life member NRA Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
Several weeks ago I read a post that stated DU Canada was anti hunting. I didn’t believe this so I went to the DU Canada site and asked them point blank; are you or are you not against hunting. Below is their answer. Jack —- SFC, USA (Ret, 1971-1993) Life member NRA (1969) Life member TSRA (1991) Member USPSA (1990) Member NROI (1991) http://home.elp.rr.com/jacksrange —- Dear Jack: Thank you for inquiring about Ducks Unlimited’s position on hunting. Ducks Unlimited Canada proudly acknowledges its hunting heritage. We recognize the ethical and sustainable recreational harvest of waterfowl as a legitimate and acceptable use of a renewable resource. It was conservation minded waterfowl hunters who established Ducks Unlimited in Canada more that 60 years ago. Their desire to ensure the long-term success of waterfowl populations defined Ducks Unlimited’s mandate. Continued support from the hunting community, and that from others interested in conserving wildlife habitat, combined with our proven ability to direct resources towards our mission has helped to establish Ducks Unlimited as the country’s most trusted and respected conservation organization. If you have attended a DU event, you will have witnessed how important hunters are to our organization. Even beyond DU, hunters are significant funders and contributors to conservation efforts across North America. We appreciate you bringing your concerns to us and providing us with an opportunity to respond. Unfortunately, every large, successful organization has its detractors. Luckily, there are individuals like you who question what you believe to be incorrect. Most sincerely, Lauralou Cicierski Communications, Ducks Unlimited Canada Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
– Hide quoted text — Show quoted text – With a little luck this year I maybe selected for an Oryx depredation hunt. In my past 35 years of hunting have hunted mule deer, whitetail deer, moose, elk, caribou, and several versions of bighorn ram not to mention smallgame like feral hog and of course upland bird. Talking with several hunting friends I am confused about how tough this animal is to bring down. I do understand the differences in the anatomy (i.e. location of the heart/lungs and the spinal cord in the neck). That aside, some say you need to use .338 Win Mag with a 200+ grain bullet because the hide is so thick, other say to can bring it down with a well placed .243 Win (this would be foolish but). I have been out on the range hunting coyote and quail and happened upon an Oryx. They show no fear of man, I’ve been able to walk to within 75 yds and all they do is look and turn away. Since they are not hunted, with the exception of these herd thinning hunts, and the fact that most if not all reside on access controlled military land they show no fear. I have been looking at using either my .280 Rem with a Sierra 160 gr SBT with a MV of about 2600 fps. However, rumor has it that the local military game management person is allowing only .30 cal and above, I’ve talked to him and pointed out that many would like to use 7mm and he received this with some enthusiasm and he said he would conceder 7mm. If the 30 cal rule prevails I’ll use my 300 Win Mag with a Sierra 165 gr SBT giving around 2800 fps. From what I’ve gleaned looking at several books on hunting African
antelope. The Oryx is much tougher than the larger kudu and most writers consider a 7mm at the very bottom of calibers to use and requiring very good shot placement. However given that, it should work. Let boys want pleasure, and men Struggle for power, and women perhaps for fame, And the servile to serve a Leader and the dupes to be duped. Yours is not theirs. "Be Angry at the Sun" Robinson Jeffers Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
With a little luck this year I maybe selected for an Oryx depredation
hunt. Ok, John, I’ll bite, just what in hell is an Oryx anyway ? Mike , just back from an unsuccessful opening day here in Ohio. Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
With a little luck this year I maybe selected for an Oryx depredation hunt. Ok, John, I’ll bite, just what in hell is an Oryx anyway ? Mike , just back from an unsuccessful opening day here in Ohio.
A large African antelope. http://www.awf.org/animals/oryx.html Let boys want pleasure, and men Struggle for power, and women perhaps for fame, And the servile to serve a Leader and the dupes to be duped. Yours is not theirs. "Be Angry at the Sun" Robinson Jeffers Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
With a little luck this year I maybe selected for an Oryx depredation hunt. In my past 35 years of hunting have hunted mule deer, whitetail deer, moose, elk, caribou, and several versions of bighorn ram not to mention smallgame like feral hog and of course upland bird. Talking with several hunting friends I am confused about how tough this animal is to bring down. I do understand the differences in the anatomy (i.e. location of the heart/lungs and the spinal cord in the neck). That aside, some say you need to use .338 Win Mag with a 200+ grain bullet because the hide is so thick, other say to can bring it down with a well placed .243 Win (this would be foolish but). I have been out on the range hunting coyote and quail and happened upon an Oryx. They show no fear of man, I’ve been able to walk to within 75 yds and all they do is look and turn away. Since they are not hunted, with the exception of these herd thinning hunts, and the fact that most if not all reside on access controlled military land they show no fear. I have been looking at using either my .280 Rem with a Sierra 160 gr SBT with a MV of about 2600 fps. However, rumor has it that the local military game management person is allowing only .30 cal and above, I’ve talked to him and pointed out that many would like to use 7mm and he received this with some enthusiasm and he said he would conceder 7mm. If the 30 cal rule prevails I’ll use my 300 Win Mag with a Sierra 165 gr SBT giving around 2800 fps. I would appreciate any input on hunting these animals. Thanks Jack SFC, USA (Ret, 1971-1993) Life member NRA (1969) Life member TSRA (1991) Member USPSA (1990) Member NROI (1991) Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
Interesting reply from DU in Canada. Quite diplomatic in its avoidance of answering your point blank question. A yes or a no is all it needed. They tell you they were founded by help from hunters, and still use hunters funds, but never say if they are against hunting. They did state they are trying to be Canada’s foremost conservation group. Not all conservation groups are pro- hunting. — Mark Life member NAHC, Endowment Life member NRA Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
Several weeks ago I read a post that stated DU Canada was anti hunting. I didn’t believe this so I went to the DU Canada site and asked them point blank; are you or are you not against hunting. Below is their answer. Jack —- SFC, USA (Ret, 1971-1993) Life member NRA (1969) Life member TSRA (1991) Member USPSA (1990) Member NROI (1991) http://home.elp.rr.com/jacksrange —- Dear Jack: Thank you for inquiring about Ducks Unlimited’s position on hunting. Ducks Unlimited Canada proudly acknowledges its hunting heritage. We recognize the ethical and sustainable recreational harvest of waterfowl as a legitimate and acceptable use of a renewable resource. It was conservation minded waterfowl hunters who established Ducks Unlimited in Canada more that 60 years ago. Their desire to ensure the long-term success of waterfowl populations defined Ducks Unlimited’s mandate. Continued support from the hunting community, and that from others interested in conserving wildlife habitat, combined with our proven ability to direct resources towards our mission has helped to establish Ducks Unlimited as the country’s most trusted and respected conservation organization. If you have attended a DU event, you will have witnessed how important hunters are to our organization. Even beyond DU, hunters are significant funders and contributors to conservation efforts across North America. We appreciate you bringing your concerns to us and providing us with an opportunity to respond. Unfortunately, every large, successful organization has its detractors. Luckily, there are individuals like you who question what you believe to be incorrect. Most sincerely, Lauralou Cicierski Communications, Ducks Unlimited Canada Visit the rec.hunting and rec.hunting.dogs FAQ Home Page at: http://sportsmansweb.com/hunting/
Response:
Categories: symptoms asthma attack children | 
No Comments »
— http://www.spectrum-computers.com http://www.webcreations-va.com Affordable Hardware, Networking, Web Hosting and Design From the Desk of Toto: Hated Oz, Took the Shoes, Went Home!! 